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Forschung bestätigt Gesundheitsrisiken von Vioxx, Bextra, Celebrex [Pharma]
17 Feb 05
 |
Forschungsergebnisse von Wellpoint Inc., der führenden US-Privatversicherung bestätigt ein höheres Risiko für Herzattacken |
New research by Wellpoint Inc., the leading US private health insurance group, has confirmed a higher risk of heart attacks with the use of painkillers such as Vioxx, Bextra and Celebrex.
In a letter to the Food and Drug Administration(FDA), Wellpoint director Samuel Nussbaum said the results of the research showed the risks of heart attacks were 53 percent higher than normal for Bextra, 23 percent for Vioxx and 19 percent for Celebrex.
By comparison, the study found no increase in heart attacks or other heart-related diseases with traditional anti-inflammatory drugs.
The research compared Wellpoint prescription records between January 2001 and June 2004 of some 630,000 patients, aged 40 and over, who did not take the drugs to a group of 7,200 who did take the COX-2 inhibitors.
"Our findings ... without adjusting for risk factors and other confounding conditions, indicate that the COX-2 class of drugs increases the risk of myocardial infarction or stroke," Nussbaum said in his letter, a copy of which was obtained by AFP.
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