Eine Studie hat die Schmerzempfindlichkeit von Migräne-geplagten Kindern untersucht. Dabei zeigte sich, dass diese häufig schmerzempfindlicher bei mechanischen oder Hitze-Reizen als Vergleichskinder sind, dies gilt insbesondere für Mädchen.
Insbesondere Mädchen mit Migräne reagierten dabei empfindlicher auf auf Wärme-Reize, wenn die Mutter beim Test anwesend war. Bei den mechanischen Reizen war es bei den kindlichen Migränikern genau umgekehrt: dann war die Reizschwelle bei Anwesenheit der Mutter höher.
Abstract:
Quantitative sensory testing in children with migraine: Preliminary evidence for enhanced sensitivity to painful stimuli especially in girls.
Recent studies showed an enhanced general sensitivity to painful stimuli in adult migraineurs during as well as between attacks. Yet, the influence of a prolonged pain history and potential sex differences has not been studied. We used quantitative sensory testing to examine 25 children with migraine between attacks and 28 controls (age 9-15). The assessment included the measurement of heat and mechanical pain thresholds as well as measures of perceptual sensitization in response to repetitive (mechanical) or tonic (thermal) noxious stimulation at both trigeminal and thenar sites. In addition, the mother was either present or absent during the measurements. Heat pain thresholds were not significantly different between the two groups. However, the child migraineurs showed significantly lower mechanical pain thresholds. Children and especially girls with migraine displayed significantly more sensitization to a tonic heat stimulus at the trigeminal site when the mother was present. The migraineurs also showed a trend towards higher sensitization ratings for mechanical stimuli. Overall, heat pain thresholds were significantly higher in the presence of the mother. In the migraine group only, mechanical pain thresholds were significantly higher when the mother was present. To summarize, an enhanced sensitivity to painful stimuli can already be observed in children suffering from migraine for an average duration of 4.4 years. This may be the result of sensitization in nociceptive pain pathways caused by frequent pain experiences. Girls with migraine were more prone to such sensitization, which may increase their risk for continuing to suffer from migraine throughout adulthood.
Zohsel K, Hohmeister J, Oelkers-Ax R, Flor H, Hermann C: Quantitative sensory testing in children with migraine: Preliminary evidence for enhanced sensitivity to painful stimuli especially in girls, Pain. 2006 Feb 20
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Anmerkung von migraeneinformation.de:
Mal abgesehen davon, dass die Studie einen ganz neuen Trigger offenbart (Mütter), zeigte sie auch, wie brav und wohlerzogen offenbar kleine Migränikerinnen sind: Bei Anwesenheit der Mutter ist eine heiße Herdplatte scheinbar noch heißer als sie es in Wirklichkeit ist. Stellt man dann trotzdem mal etwas an und erhält von der Mutter einen kleinen Klaps, dann wird vorher die Schmerzempfindlichkeit gesenkt...
