827 Migränepatienten wurden bzgl. der Rückbildungsphase (Postdrom-Phase) ihrer Migräne analysiert. Die Resultate:
- 68% der Betroffenen klagten über eine Rückbildungsphase.
- Die Rückbildungsphase dauerte durchschnittlich 25,2 Stunden.
- Das häufigste Symptom war Müdigkeit (71,8%).
- Als weitere Symptome folgten Kopfschmerzen (33,1%), kognitive Probleme (11,7%), Kater (10,7%), Magen/Darmprobleme (8,4%), Stimmungsschwankungen (6,8%) und Schwäche (6,2%).
Patienten mit deutlicher Rückbildungsphase litten unter charakteristischeren und häufigeren Migränesymptomen als Betroffene ohne Postdrom-Phase.
Abstract:
The postdrome of the acute migraine attack
L Kelman1
Kelman L. The postdrome of the acute migraine attack. Cephalalgia 2005. London. ISSN 0333-1024
This study was performed to document the frequency, duration and types of symptoms of postdrome in migraine patients. Eight hundred and twenty-seven consecutive headache clinic patients (IHS 1.1, 1.2 and 1.5.1) were evaluated at first visit. Postdrome frequency, duration and characteristics were analysed. Sixty-eight per cent of 827 patients reported postdrome (69.1% females; 56.8% males, P < 0.007). The average duration of the postdrome was 25.2 h. Fifty-six per cent had postdrome for 12 h, 32% for 1224 h, 88% for 24 h, and 12% for > 24 h. The commonest symptoms were tiredness (71.8%), head pain (33.1%), cognitive difficulties (11.7%), 'hangover' (10.7%), gastrointestinal symptoms (8.4%), mood change (6.8%), and weakness (6.2%). Patients with postdrome compared with patients without postdrome have more characteristic and more frequent migraine features. This study demonstrated postdrome in 68% of patients, duration 24 h in most patients, more often associated with a full-blown migraine attack, more common in females, and with commonest symptoms being tiredness and low-grade headache.
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